Igor Stefanini

About

Lecturer and Senior researcher at the SUPSI. Currently he is the head of Medical Devices group at SUPSI-DTI-MeDiTech, where his academic research interests, mainly carried out in cooperation with Swiss industrial and academical partners, are focused on precision micro-technical systems and technologies for biomedical applications, particularly in the field of clinical & regenerative medicine. He’s responsible for Bachelor courses in Medical Technologies, for Master MSE courses in Biology, physiology and anatomy for engineers and student’s advisor at the same Master program. He earned a PhD in science at EPFL in 2006. So far, he led/participated at several applied and fundamental research projects with 1 SNSF project, 15 CTI/INNOSUISSE projects, 1 EUROSTARS/EUREKA project and more 30 direct mandates from third parties and private foundations, engendering 7 patents applications and more 40 national and international publications. He has already been independent expert appointed by the CP Start-Up (AGIRE Foundation) at the STARTCUP TICINO initiative program, coach appointed by the AGIRE Foundation for the annual Start-up Accelerator Program, coordinator of the Research Line in Biomedical Technologies at SUPSI-DTI, Director of the Foundation for Cardiological Research and Education (FCRE) and of the Swiss Institute for Regenerative medicine (SIRM) managed by FCRE, and research Coordinator and supervisor of the Cardiocentro Ticino Foundation (FCCT) research projects focused in Advanced Therapies and Biomedical Engineering. In previous research activities he has collected a deepened knowledge in different technological fields applied in the development of biomedical systems and devices, in particular for: 1) Valves - With the development of customer valves for different medical devices to manage the liquid like blood, medium or gas like air, oxygen, etc. 2) Microfluidic device and management - For performing the isolation, the detection and the quantification of exosomes secreted by cardiomyocytes cultivated in a customer bioreactor or real-time detect of different virus like: SARS-CoV-2, Zika, Dengue or Chikungunya and based on multifunctional silica membrane microfluidic biosensors. Another applied field is focused on dispensing active principle using in Dry-eyes syndrome therapy. 3) Miniature spectrometer and LED - Combined optoelectronics absorption spectroscopy and colorimetry methods for detecting liquid phase changes and recognising the type of liquid treated. This knowledge extends to optoelectronics methods for indirect pH measurements. Another field of deep knowledge related to optoelectronics is the photo-pletismography for acquiring blood’s O2 concentration and cardiac rhythms. 4) Bio-impedance measurement - With the applications in cell growth curve analysis (capacity effect, dielectric characterisation) using to detect impedance, in particular, phases and module of cell culture or part of biological tissue in liquid suspension. 5) Measurement methodology – With a deepened knowledge especially in all applications where the analytical or empirical models have been developed to understand physical phenomena under study. 6) Drive and acquisition electronics - Developed in all projects to manage the information and produce the correct actuations. 7) Actuators - Deepened knowledge in motors used in centrifugation process, or heating systems to control particular temperature; massager planar oscillator, mechano-sound vibration, micro vacuum and diathermy.

Work

IGAN Group SA

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Owner and CTO

Switzerland

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SUP della Svizzera italiana - SUPSI

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Group leader

Switzerland

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Theralip SA

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Owner and CTO

Switzerland

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C-Over Technologies Swiss Sagl

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Owner and CTO

Switzerland

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SUP della Svizzera italiana - SUPSI

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Co-head of the institute

Switzerland

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SUP della Svizzera italiana - SUPSI

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Group leader

Switzerland

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SUP della Svizzera italiana - SUPSI

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Head of the laboratory

Switzerland

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SUP della Svizzera italiana - SUPSI

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Biosecurity officer (BSO) at the experimental facility of the LSIB

Switzerland

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SUP della Svizzera italiana - SUPSI

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DTI-MEDtech area delegate at the SUPSI Research Strategy Group (GSR)

Switzerland

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AGIRE Foundation

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Coach appointed for the annual Start-up Accelerator Program

Switzerland

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AGIRE Foundation

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CP Start-Up Independent expert for the preselection projects at STARTCUP TICINO

Switzerland

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Istituto Cardiocentro Ticino

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Area Manager for SUPSI projects at the FCCT, FCRE and SIRM

Switzerland

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SUP della Svizzera italiana - SUPSI

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Coordinator of the Research Line in Biomedical Technologies at SUPSI-DTI

Switzerland

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Foundation for Cardiological Research and Education (FCRE)

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Head of the institute

Switzerland

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Foundation for Cardiological Research and Education (FCRE)

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Head of the foundation

Switzerland

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Istituto Cardiocentro Ticino

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Research Coordinator at the Cardiocentro Ticino Foundation (FCCT)

Switzerland

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SUP della Svizzera italiana - SUPSI

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Group leader

Switzerland

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SUP della Svizzera italiana - SUPSI

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Research associate / Scientific collaborator

Switzerland

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École Polytechnique Fédérale de Lausanne

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Junior researcher / Postdoc

Switzerland

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École Polytechnique Fédérale de Lausanne

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Doctoral student / PhD student

Switzerland

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Education

FOEN, FOPH, SUVA, SECB and ERFA BIO

Switzerland
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Certificate of BSO biosafety level 1

SUP della Svizzera italiana - SUPSI

Switzerland
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Certificate of Advanced Studies (CAS) in didactics SUPSI - SEDIFO service

SUP della Svizzera italiana - SUPSI

Switzerland
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Internal auditors according to ISO 19011:2012 at the SUPSI Quality Service

SUP della Svizzera italiana - SUPSI

Switzerland
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Fund a project, collaborate successfully with sponsors and donor foundations

École Polytechnique Fédérale de Lausanne

Switzerland
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Postdoc - Optimisation of power consumption and miniaturisation of Lavet motor

École Polytechnique Fédérale de Lausanne

Switzerland
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PhD / Dr.: Docteur ès science EPFL

École Polytechnique Fédérale de Lausanne

Switzerland
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Bachelor and Master: Engineer in electricity (MSc)

HES-SO Vaud

Switzerland
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Bachelor: Engineer in electricity (BSc)

HES-SO Vaud

Switzerland
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Fundamental Principles of Space Techniques by Swiss Space Association (SRV)

Publications

Current state of the art on implantable sensors for continuous post-EVAR surveillance of abdominal aortic aneurysms: A comprehensive review

Biosensors and Bioelectronics X

journal-article

DNA-biosensors for reaching attomolar detection of viruses from saliva

World Congress on Biosensors 2023

conference-paper

A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus

Biosensors and Bioelectronics: X

journal-article

Detection in a Non-invasive Way of Glucose in Cells Cultivation

2019 E-Health and Bioengineering Conference (EHB)

conference-paper

Detection in a Non-invasive Way of Glucose in Cells Cultivation

2019 E-Health and Bioengineering Conference (EHB)

conference-paper

Detection in a non-invasive way of glucose in cells cultivation

2019 7th E Health and Bioengineering Conference Ehb 2019

conference-paper

EXODEVICE: Continuous Perfusion Large Scale Exosome Cultivation Bioreactor

2019 E-Health and Bioengineering Conference (EHB)

conference-paper

EXODEVICE: Continuous perfusion large scale exosome cultivation bioreactor

2019 7th E Health and Bioengineering Conference Ehb 2019

conference-paper

Smart Modular Bioreactor Prototype

2019 E-Health and Bioengineering Conference (EHB)

conference-paper

Adaptive Bio-impedance Measurement

2019 E-Health and Bioengineering Conference (EHB)

conference-paper

Adaptive bio-impedance measurement

2019 7th E Health and Bioengineering Conference Ehb 2019

conference-paper

Smart modular bioreactor prototype

2019 7th E Health and Bioengineering Conference Ehb 2019

conference-paper

Fatshake: Device for producing globules of adipose tissue

2019 7th E-Health and Bioengineering Conference, EHB 2019

conference-paper

Dispositivo di produzione di globuli di tessuto adiposo.

patent

Counting Cells in Time-Lapse Microscopy using Deep Neural Networks

preprint

Counting cells in time-lapse microscopy using deep neural networks

arXiv

other

Processo e dispositivo per produrre esosomi.

patent

X-rays transparent resuscitator system for percutaneous transluminal coronary angioplasty

2015 E Health and Bioengineering Conference Ehb 2015

conference-paper

Power transfer for rotating medical machine

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

conference-paper

Blood extractor - Medical device for standardized and optimized cord blood extraction

2015 E-Health and Bioengineering Conference, EHB 2015

conference-paper

A Colorimetric Method to Isolate Adipose Derived Stem Cells

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Alternative Self-Powering Source for Implantable Medical Devices

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Wireless power transfer for rotating medical machines

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Dispositivo di sostegno per la rianimazione cardio polmonare e metodo per l'assistenza di un operatore durante la rianimazione cardio polmonare.

patent

X-rays transparent resuscitator system for percutaneous transluminal coronary angioplasty

2015 E-Health and Bioengineering Conference (EHB)

conference-paper

Automatic mechanical resuscitator for catheterism room

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Standardised and Optimised Cord Blood Extractor

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Supporting device for cardiopulmonary resuscitation and method for the assistance of an operator during pulmonary resuscitation

International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC)

conference-poster

Dispositivo portatile di recupero di energia elettrica.

patent

Dispositivo di dialisi.

patent

Dispositivo di raccolta di sangue

patent

Massaggiatore cardiaco automatico per l’utilizzo in sale di cateterismo.

patent

Contactless system dedicated to colic stimulation

2008 18th International Conference on Electrical Machines

conference-paper

Contactless system dedicated to colic stimulation

Proceedings of the 2008 International Conference on Electrical Machines, ICEM'08

conference-paper

Optimization of a biomedical actuator for implantable countinuous glucose monitoring

Conference Record - IAS Annual Meeting (IEEE Industry Applications Society)

conference-paper

Méthodologie de conception et optimisation d'actionneurs intégrés sans fer

Lausanne, EPFL

dissertation-thesis

3D Numerical Model of Subcutaneous Insulin Micro-Pump Infusion System

International Symposium on Linear Drivers for Industry Applications (LDIA)

conference-poster

3D inductance and impedance determination taking skin effect into account

2005 IEEE International Conference on Electric Machines and Drives

conference-paper

3D torques, translational forces and induced voltage determination in an ironless biomedical actuator

2005 European Conference on Power Electronics and Applications

conference-paper